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as a color-banded ruler, with the numerical axis the representing number of amino acid residues from N-terminus to C-terminus.\nThis example shows the protein translated from the preferred isoform of ",{"type":430,"tag":451,"props":452,"children":453},"em",{},[454],{"type":435,"value":455},"TP53",{"type":435,"value":457}," gene (NM_000546), shown on the top left.\nClick the gene symbol to view all isoforms for ",{"type":430,"tag":451,"props":459,"children":460},{},[461],{"type":435,"value":462},"TP53:",{"type":430,"tag":431,"props":464,"children":465},{},[466],{"type":430,"tag":440,"props":467,"children":470},{"alt":468,"src":469},"image 5","/img/visualization-community/proteinpaint/getting-started/image5.png",[],{"type":430,"tag":431,"props":472,"children":473},{},[474],{"type":435,"value":475},"To view a different protein isoform, either click on the diagram of the isoform in above panel, or search by the isoform's RefSeq accession number instead of gene symbol.",{"type":430,"tag":477,"props":478,"children":480},"h3",{"id":479},"protein-domain",[481],{"type":435,"value":482},"Protein domain",{"type":430,"tag":431,"props":484,"children":485},{},[486],{"type":435,"value":487},"The source of protein domain annotation is primarily the NCBI CDD database, which has been supplemented by in-house curation efforts.\nIn ProteinPaint, domains are represented by color bands, with varying colors indicating different types of domains.\nThe list of domain types is shown in the legend according to their order of appearance on the protein.\nFor manually curated domains, a PubMed link may be available to reference the source publication.",{"type":430,"tag":431,"props":489,"children":490},{},[491],{"type":430,"tag":440,"props":492,"children":495},{"alt":493,"src":494},"image 3","/img/visualization-community/proteinpaint/getting-started/image3.png",[],{"type":430,"tag":431,"props":497,"children":498},{},[499],{"type":435,"value":500},"Hovering the cursor over the protein will display a tooltip showing any domains under the cursor (in some cases there can be more than one):",{"type":430,"tag":431,"props":502,"children":503},{},[504],{"type":430,"tag":440,"props":505,"children":508},{"alt":506,"src":507},"image 2","/img/visualization-community/proteinpaint/getting-started/image2.png",[],{"type":430,"tag":431,"props":510,"children":511},{},[512],{"type":435,"value":513},"As a convenience, ProteinPaint offers an option to hide selected domains.\nTo hide a domain type, click on one of the colored boxes in the legend to hide all occurrences of the selected type of domain from display.\nAn \"x\" sign will appear inside the box to indicate a domain has been hidden.\nFollowing example shows TP53 protein with three types of domain hidden:",{"type":430,"tag":431,"props":515,"children":516},{},[517],{"type":430,"tag":440,"props":518,"children":521},{"alt":519,"src":520},"image 6","/img/visualization-community/proteinpaint/getting-started/image6.png",[],{"type":430,"tag":431,"props":523,"children":524},{},[525],{"type":430,"tag":440,"props":526,"children":529},{"alt":527,"src":528},"image 7","/img/visualization-community/proteinpaint/getting-started/image7.png",[],{"type":430,"tag":431,"props":531,"children":532},{},[533],{"type":435,"value":534},"Hidden domains will be excluded from screenshots.\nClick the box marked by \"X\" to toggle the domain visible again.",{"type":430,"tag":477,"props":536,"children":538},{"id":537},"exon-junction",[539],{"type":435,"value":540},"Exon junction",{"type":430,"tag":431,"props":542,"children":543},{},[544],{"type":435,"value":545},"When hovering the cursor over the protein, the tooltip indicates the amino acid residue under the cursor, and the associated exon number:",{"type":430,"tag":431,"props":547,"children":548},{},[549],{"type":430,"tag":440,"props":550,"children":553},{"alt":551,"src":552},"image 12","/img/visualization-community/proteinpaint/getting-started/image12.png",[],{"type":430,"tag":431,"props":555,"children":556},{},[557],{"type":435,"value":558},"Dashed lines represent exon junctions.\nThe following example shows an exon junction is overlaps with Alanine 307, which is marked by exon numbers 8 and 9:",{"type":430,"tag":431,"props":560,"children":561},{},[562],{"type":430,"tag":440,"props":563,"children":566},{"alt":564,"src":565},"image 11","/img/visualization-community/proteinpaint/getting-started/image11.png",[],{"type":430,"tag":431,"props":568,"children":569},{},[570],{"type":435,"value":571},"To show additional details about A307, click on this position and ProteinPaint will zoom in to show that the exon junction falls inside codon A307, between the first and second nucleotides.\nThe codon nucleotides are shown in the top row, and amino acid residues are shown in the middle.\nAlternating background shades help distinguish adjacent codons.\nDuring zoom-in, the 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